ReBrain: A Database for Broad-Spectrum Drug-Repurposing against Brain Cancer

Introduction:
Explore drug-repurposing against brain cancer with 2809 FDA-Approved molecules (MW<=500D). Relationships are being established with predicted activity weightage from 15-SAR properties for respected target/ cell-line as: U87, BRAF, EGFR, MGMT, PDGFRA, TERT, TP53, CDK1, CDK2, CDK3, CDK4, COX1, COX2, VEGFR2, and CYP2D6. It includes cancer cell line, anti-cancer therapeutic targets, Cell-cycle observation, anti-inflammatory activity observation, anti-angiogensis, and metabolism observation.

Select Query-Drug

Select Targets/ Cell-Line for Brain Cancer (Knock-Out Experiments can be performed by Uncheck)

MW Similarity (%)

1%
0.03