This framework comprises two custom applications. The first, in-mac, is a profile-generation engine that computes computational bioassay-based activity signatures for small molecule across 15 pathway-relevant components. The second, ReBrain, is a database for broad-spectrum drug-repurposing analytics. It is hypothesized that FDA-approved drugs capable of modulating these pathways could induce therapeutically meaningful shifts in oncogenic network states. This hypothesis suggests opportunities for drug-repurposing across diverse brain cancer types.
The ReBrain Database provides a structured repository intended to support neurological and brain-related research efforts. The platform enables users to explore curated datasets and reference material in an open-access environment.
Access URL:
https://assay.smallmoles.com/escorwin/rebrain/rebrain.html
Access Status: Free in public domain
The in-mac Profile Generator is an openly accessible analytical tool designed to generate structured profiles for research and exploratory analysis, with demonstrated application in brain cancer–related data interpretation.
Access URL:
https://assay.smallmoles.com/escorwin/inmac/braincancer.html
Access Status: Free in public domain
Public Access-Key: password